Efficacy and safety of topical WBI-1001 in the treatment of atopic dermatitis: results from a phase 2A, randomized, placebo-controlled clinical trial.

نویسندگان

  • Robert Bissonnette
  • Genhui Chen
  • Chantal Bolduc
  • Catherine Maari
  • Michael Lyle
  • Liren Tang
  • John Webster
  • Youwen Zhou
چکیده

explain unique variance associated with sunbathing intentions and intentions to sun protect. For both analyses, age, sex, skin type, and perceived susceptibility were entered in step 1, followed by the 3 appearance-based tanning motives (appearance reasons to tan, appearance reasons not to tan, and sociocultural influences) entered in step 2. The overall R for both analyses was significant and indicated that a high level of variance was accounted for by the predictors (sunbathing R=.50; sun protection R=.62). In both regressions, appearance subscales of the PARTS explained significant variance beyond that explained by age, sex, skin type, and perceived susceptibility (Table). Appearance reasons to tan were significantly associated with sunbathing intentions (P .01) but not with sun protection intentions (P=.07): adolescents who positively endorsed appearance reasons to tan also reported more frequent intentions to sunbathe in the next 12 months and fewer intentions to sun protect. Appearance reasons not to tan were significantly associated with sunbathing intentions (P=.03) and with sun protection intentions (P .01): participants scoring higher on appearance reasons not to tan also reported fewer intentions to sunbathe and higher intentions to sun protect.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The efficacy of topical Sucralfate in comparison with Hydrocortisone cream in the treatment of Diaper dermatitis: A randomized, double blind clinical trial

Background: Topical corticosteroids are currently used for treatment of diaper dermatitis. Previous studies have shown the efficacy of sucralfate in the treatment of diaper dermatitis and contact dermatitis in peri-stomy areas. Objectives: To evaluate the efficacy of topical sucralfate in comparison with hydrocortisone cream in the treatment of diaper dermatitis. Patients and Methods: In a doub...

متن کامل

Efficacy of Melaleuca alternifolia Essential Oil in the Treatment of Facial Seborrheic Dermatitis: A Double-blind, Randomized, Placebo-Controlled Clinical Trial

Background: Melaleuca alternifolia (tea tree) essential oil has been traditionally used in the ayurvedic system of medicine for healing burns, infections and seborrheic dermatitis. But yet, no controlled human study has determined its efficacy. Objective: The goal of the current study was to compare the efficacy of 5% tea tree essential oil (TTO) gel with placebo in the treatment of mild to m...

متن کامل

Topical Channa striatus 5% cream for inflammatory skin conditions: A phase I randomized double-blind, controlled trial

Background: Channa striatus or better known as the haruan fish is an indigenous, snakehead, striped, air breathing freshwater fish of Malaysia and has long been consumed traditionally during post-operative and post-partum period to speed recovery. Most medical properties of the haruan are contributed to its high content of essential fatty and amino acids. This was a phase I clinical trial to ex...

متن کامل

Comparison of the efficacy of Fluocinolone cream, Triclocarban soap and Betamethasone lotion with placebo in the treatment of Paederus Dermatitis

Background and aim: Paederus dermatitis is an acute self-healing blistering disease caused by an insect from the genus Paederus species. Although it is a self-limited disease, it can cause disablement and suffering. The objective of this study was to investigate the efficacy of fluocinolone cream, triclocarban(TCC) soap and betamethasone lotion in comparison with placebo in the treatment ...

متن کامل

Evaluation of the efficacy of topical Caffeine in the treatment of Psoriasis Vulgaris: A randomized, double-blind clinical trial

Background and aim: Psoriasis is one of the most common papulosquamous diseases that often requires long-term maintenance therapy. Long-term use of topical corticosteroids on the face and intertriginous areas will increase the risk of steroids side effects such as striae and atrophy development. A safe, effective and inexpensive modality in topical therapy of inverse psoriasis is required...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Archives of dermatology

دوره 146 4  شماره 

صفحات  -

تاریخ انتشار 2010